Will one C+ affect college?

I am in highschool and I earned straight As except for one C+ that I earned in middle school for highschool credit. Will this affect getting into a re

I am in highschool and I earned straight A's except for one C+ that I earned in middle school for highschool credit. Will this affect getting into a really really good college?

or:I am in highschool and I earned straight A's except for one C+ that I earned in middle school for highschool credit. Will this affect getting into a really really good college?

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