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2022-10-25 00:28:43

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2022-10-25 00:28:43

AboutApplicationsCollaboratorsPlatformContact UsSelect Page Better Treatment Demands Better MeasurementSPARK Neuro combines patented neural metrics with advanced machine learning algorithms in the SPARK Scan, a 10-minute EEG-based evaluation that identifies the first signs of changes in the brain, advancing therapeutic discovery and clinical care.ABOUTNeuroscience Meets Artificial IntelligenceIn partnership with the most prestigious institutions in the world, SPARK Neuro enables a new era of analyzing brain activity to better understand diseases of the central nervous system.VISION: A world where measuring and caring for brain health is universally accessible.MISSION: To revolutionize brain measurement for better clinical care and therapeutic discovery through SPARK Neuro’s AI technology.APPLICATIONSMore Objective Answers at the Earliest StagesSPARK Neuro builds diagnostic and monitoring applications for more accurate and objective measurement of brain-based diseases.Drug DevelopmentSPARK’s Drug Development Dashboard provides early insights for clinical trials, saving time and money throughout the course of drug development. The Dashboard can increase the success of central nervous system (CNS) therapeutic trials through brain-based measures for:Early signs of efficacy: De-risk future stage drug trials by measuring the earliest neurological signs of efficacyPopulation stratification: Uncover distinct patient traits that predict drug response vs. non-responsePharmacodynamics: Examine if the drug crosses the blood-brain barrier (BBB) and engages the intended targetDosing: Identify the optimal dose range, including the minimum dose to produce a neural responseClinical CareSPARK Neuro is currently conducting clinical studies for the diagnosis and monitoring of:Mild Cognitive Impairment (MCI) and DementiaAlzheimer’s DiseaseDementia with Lewy BodiesParkinson’s DiseaseMultiple System AtrophyFrontotemporal DementiaNormal Pressure HydrocephalusBrain InjuriesMental health conditions, including Depression, Anxiety, PTSD, ADHD, and SchizophreniaAPPLICATIONSMore Objective Answers at the Earliest StagesSPARK Neuro builds diagnostic and monitoring applications for more accurate and objective measurement of brain-based diseases.Drug DevelopmentClinical CareSPARK’s Drug Development Dashboard provides early insights for clinical trials, saving time and money throughout the course of drug development. The Dashboard can increase the success of central nervous system (CNS) therapeutic trials through brain-based measures for:Early signs of efficacy: De-risk future stage drug trials by measuring the earliest neurological signs of efficacyPopulation stratification: Uncover distinct patient traits that predict drug response vs. non-responsePharmacodynamics: Examine if the drug crosses the blood-brain barrier (BBB) and engages the intended targetDosing: Identify the optimal dose range, including the minimum dose to produce a neural responseSPARK Neuro is currently conducting clinical studies for the diagnosis and monitoring of:Mild Cognitive Impairment (MCI) and DementiaAlzheimer’s DiseaseDementia with Lewy BodiesParkinson’s DiseaseMultiple System AtrophyFrontotemporal DementiaNormal Pressure HydrocephalusBrain InjuriesMental health conditions, including Depression, Anxiety, PTSD, ADHD, and SchizophreniaCOLLABORATORSAdvanced Scientific DiscoveryMayo ClinicSPARK Neuro’s formal collaboration, ongoing research efforts, and grant co-awards with Mayo Clinic are core to our methods for developing advanced diagnostic technology for neurological disorders.US GovernmentSPARK’s ability to advance scientific discovery is underpinned by extensive National Institutes of Health (NIH) grants, Department of Defense (DoD) funding, US Army Medical awards, and US Air Force contracts.Other CollaboratorsWe have numerous collaborations with prestigious clinical, research, and academic institutions, including Johns Hopkins, University of Oxford, Providence Health, Massachusetts Institute of Technology, and numerous neurology and psychiatry clinics.PLATFORMAdvanced TechnologySPARK combines the power of neurological data with advanced machine learning to develop highly sensitive and specific measures of cognitive function and CNS diseases.Electroencephalography (EEG)EEG data is an incredibly rich signal, providing about 1 million observations of brain activity data per minute. However, the richness of that signal comes with complexity beyond what the human eye can see, limiting the ability to provide meaningful insights with traditional approaches.Using FDA cleared EEGs, SPARK Neuro combines the power of modern cloud computing and advanced analytic techniques, enabling us to peer deeper into brain function.Machine Learning AlgorithmsOur platform’s artificial intelligence (AI) infrastructure unlocks the full potential of EEG by harnessing machine learning (ML) and advanced deep-learning techniques to decode this highly complex array of brain activity signals.This approach allows us to develop algorithms for objective measurement of cognitive disorders and to provide clinical and pharmacological insights with superior diagnostic accuracy.User Friendly SoftwareOur intuitive, end-to-end software guides experts and non-experts alike through a few simple steps, allowing any user the ability to run a SPARK Scan with the push of a button.The software automatically transmits test results to the cloud where data is processed by our ML pipelines, returning an interactive report in seconds.PLATFORMAdvanced TechnologySPARK combines the power of neurological data with advanced machine learning to develop highly sensitive and specific measures of cognitive function and CNS diseases.Electroencephalo-graphy (EEG)EEG data is an incredibly rich signal, providing about 1 million observations of brain activity data per minute. However, the richness of that signal comes with complexity beyond what the human eye can see, limiting the ability to provide meaningful insights with traditional approaches.Using FDA cleared EEGs, SPARK Neuro combines the power of modern cloud computing and advanced analytic techniques, enabling us to peer deeper into brain function.Machine LearningAlgorithmsOur platform’s artificial intelligence (AI) infrastructure unlocks the full potential of EEG by harnessing machine learning (ML) and advanced deep-learning techniques to decode this highly complex array of brain activity signals.This approach allows us to develop algorithms for objective measurement of cognitive disorders and to provide clinical and pharmacological insights with superior diagnostic accuracy.User FriendlySoftwareOur intuitive, end-to-end software guides experts and non-experts alike through a few simple steps, allowing any user the ability to run a SPARK Scan with the push of a button.The software automatically transmits test results to the cloud where data is processed by our ML pipelines, returning an interactive report in seconds.Contact UsIf you are a pharmaceutical professional, researcher, or clinician working with neurological or psychiatric disorders, please don’t hesitate to reach out.This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply. 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